It is well-established that systemic sclerosis (SSc) is a chronic, autoimmune progressive connective tissue disorder often characterized by extensive vascular, immune, and fibrotic changes of the skin and internal organs. However, there is less evidence for the associations between femoral cartilage thickness (FCT), vitamin D levels, and SSc-disease parameters. In this regard, a recent study demonstrated that SSc patients showed thinner femoral cartilage values when compared with control.

Moreover,  a significant difference was seen in the measurement of right intercondylar area (p=0.029), right medial condyles (p=0.022), left intercondylar area (p=0.036), left lateral condyle, and left medial condyle (p=0.001) amongst patients and control. Also, SSc patients displayed significantly lower levels of vitamin D when compared with controls. Thus, this study emphasizes the relation between…