A 65-year-old man with severe hypertension has not achieved his therapeutic goal for controlling his blood pressure after treatment with a combination of four different antihypertensive drugs for the past six months. Having exhausted the list of the most highly recommended drugs, his physician elects to add reserpine to his drug regimen, since it has a unique mechanism of action, and remains as a therapeutic option based upon the consensus of expert opinions for treatment of hypertension.

*This case is from the Docplexus Editorial Team for educative purposes only.