A woman in her 40s presented with diffused abdominal pain, meteorism and intermittent diarrhoea. Gastrointestinal workup including abdominal computed tomography (CT) and magnetic resonance imaging (MRI) scans revealed a focal rounded lesion in segment IV of the liver without any edema or reactive changes. Although there was no history of progesterone or estrogen therapy, the radiographic appearance was considered to be suggestive of adenoma.

The lesion was monitored by ultrasound after 3 years when a resection of hepatic segment VI was performed because of the presumed risk of a malignant transformation. The lesion was excised and intraoperatively found to be surrounded by 3 smaller satellite nodules, located close to the liver capsule, the parietal peritoneum and infiltrating the diaphragm. Histological Exam: Histological examination of H&E stained sections revealed a densely cellular…