The β-lactam monotherapy is equally effective than β-lactam plus macrolide combination therapy in hospitalized children with pneumonia, shows results of a recent clinical study published in the JAMA Pediatrics. This study further states that the current empirical combination therapy may lead to antibiotic resistance. Pneumonia is the major infectious cause of mortality among children under five.
The most common empirical therapy used for the management of hospitalized patients with pneumonia is β-Lactam monotherapy and β-lactam plus macrolide combination therapy. The effectiveness of these 2 treatment modalities is not well evaluated by many clinical studies . Study design The multicenter, prospective, population-based study included 1418 children (up to 18 years of age) who were hospitalized with radiographically confirmed pneumonia and who received β-lactam monotherapy or β-lactam…
