A 26-year-old woman with a history of iron deficiency anemia presented to the emergency department with fatigue, abdominal pain and an 18-month history of significant weight loss (100 pounds). She also experienced night-sweats and had a nearly six-month history of voluminous diarrhea. The patient presented to other hospitals before coming to present hospital, but a proper workup for her was deferred due to financial concerns. Computerized tomography scans demonstrated left-retroperitoneal lymphadenopathy, in addition to bulky lymphadenopathy in the left inguinal, pelvic and external iliac chains.
The largest lymph node was approximately 6.1 cm in greatest dimension. Initial biopsies were not definitive for lymphoma. Eventually, a biopsy demonstrated scattered, large, atypical cells in a polymorphous inflammatory background (Refer to images attached). What is the likely diagnosis based…
