Preeclampsia (PE) is a major cause of maternal and perinatal morbidity and mortality and is thought to be predominantly as the consequence of impaired placentation. A major challenge in modern obstetrics is early identification of pregnancies at high-risk of early onset PE and undertaking the necessary measures to improve placentation and reduce the prevalence of the disease. Hence Effective screening for the development of early-onset preeclampsia (PE) can be provided in the first-trimester of pregnancy.
Evidence suggests that PE can be subdivided into early onset PE, requiring delivery before 34 weeks' gestation and late onset PE, with delivery at or after 34 weeks, because the former is associated with a higher incidence of adverse outcome. A major challenge in modern obstetrics is early identification of pregnancies at high-risk of early onset PE and undertaking the necessary…
