The WHO anticipates that by the year 2050, the population of older adults will exceed 2.1 billion. Therefore, there is an urgent need to identify strategies to improve health during the process of aging as age-associated defects can lead to several diseases and disorders, affecting the quality of life of the geriatric population significantly. Mitochondrial dysfunction and elevated oxidative stress are key contributors to aging; therefore, antioxidants, such as glutathione (GSH), could be beneficial in improving or delaying the hallmarks of aging.

Researchers at Baylor College of Medicine, USA, have studied how supplementation with GlyNAC, a combination of GSH precursor amino acids glycine and cysteine, improves many age-associated defects in older humans and promotes healthy aging. The restoration of mitochondrial health and correction of oxidative stress with GlyNAC supplementation…