Case presentation A 43-year-old male with Crohn's disease (CD) since 2008 presented with back pain and ecchymosis on his left leg and abdomen (Figure 1). Figure 1.
Ecchymosis observed in the patient Medical history On azathioprine and mesalamine treatment for CD; however, the patient failed to adhere to the regimen In 2012, the patient developed erythematous mucosa in the gastric antrum, rectal to cecal friability, and superficial ulcers In 2014, the patient developed multiple aphthoid ulcers extending from the rectum to the cecum and persistent ileocecal valve stenosis Treated with infliximab from 2014 to 2020, resulting in symptom control Following the recurrence of symptoms, the patient was treated with vedolizumab and then with prednisone until February 2024 Laboratory tests Thrombocytopenia Elevated levels of D-dimer and lactate dehydrogenase Peripheral smear analysis – Atypical…
