Ovarian cancer often occurs in perimenopausal women. Its mortality rate ranks first in gynecological tumors. The main screening methods are transvaginal ultrasonography, serum CA-125 and so on.
Due to the variety of pathology and not clear enough of mechanism and etiology, there are still no ideal tumor markers with both high specificity and sensitivity, which can be applied into clinical early diagnosis for ovarian cancer. Therefore, a new systematic method with high sensitivity and specificity for an early diagnosis of ovarian cancer and new tumor markers need to be identified. Considering the above fact, what are the advances in tumor markers of ovarian cancer for early diagnosis?
