A 48-year old healthy woman presented to a clinic with a 6-month history of an irritating sensation on her left lateral tongue. The lesion was neither painful nor factitial in nature; however, the lesion was sore or irritating at times. The patient did not report any ulceration or bleeding at the site of the lesion. The patient had an unremarkable medical history.

She had no drug or food allergies and had no history of smoking, alcohol consumption, or illicit drug use. However, she had a frequent habit of chewing gums. Clinical Examination Ragged, patchy, white plaque on the left lateral tongue that could not be wiped off (Fig. 1) Absence of bleeding, ulceration, or any evidence of induration on palpation Natural dentition, with no fractured teeth or sharp restorations next to the lesion Absence of oral mucosal lesions Sufficient salivary output on visual inspection Incisional Biopsy…