Nature of gut microbes determines the formation of Aβ amyloid plaques in brain. Alzheimer’s Diseases (AD) is the most common cause of dementia resulting in loss of memory as well as change in behavior and thinking pattern. In the modern day, AD is becoming an ever-growing socio-economic burden. As per the results of clinical investigations, deposition of amyloid-β (Aβ) peptides into extracellular amyloid plaques is an early event triggering the pathological cascade for dementia.
Thus, the most rational strategy to fight AD is to retard or halt the formation of Aβ formation. Unfortunately, despite of all the research efforts there is no available treatment for this disease. All the current treatment strategies are focused towards symptomatic therapies. Microbiota and its role in several diseases: In several studies, it has been reported that microbial community plays an essential role…
