Low tissue oxygen levels in anemia leads the kidney to produce erythropoietin which stimulates the bone marrow to produce RBCs. The major cause of anemia in chronic kidney disease (CKD) is a reduction in erythropoietin production due to kidney damage. This results in reduced oxygen utilization, increased cardiac output and left ventricular hypertrophy, reduced cognition and concentration, reduced libido and reduced immune responsiveness.
The attached guidance covers the management of anemia in adults, children and young people with a clinical diagnosis of anemia associated with CKD. Broadly the guidance focusses on: Factors Responsible in development of anemia in CKD – including deficiency of erythropoietin, iron, folate, or vitamin B12; blood loss; infection; and inflammation Diagnosis, Monitoring & Management: Recognizing anemia by monitoring the blood count as well as glomerular…
