In India, breast cancer takes the lead as the most prevalent cancer among women, contributing to a significant 13.5% of all cancer cases, according to the Global Cancer Observatory (GLOBOCAN) data from 2020. 1 What's interesting is that 10% of these breast cancer cases have a hereditary component, arising from specific genetic variations called pathogenic variants (PVs) of breast cancer antigen genes, namely BRCA1 and BRCA2. These mutations can significantly impact a person's risk, with individuals carrying BRCA mutations having a 60% chance of developing breast cancer by the age of 70.
Understanding the genetic factors underlying breast cancer paves the way for improved prevention and care. 2 This infographic discusses a case-control study that used NGS for BRCA mutation detection and the significance of this genetic testing in breast cancer patients. ##References## GLOBOCAN 2020…
