Idiopathic male infertility is one of the major concerns in the field of reproductive health because of its unknown etiology and hence diagnosis and management. A new terminology – Male oxidative stress infertility has been coined to address this issue. In spite of the reproductive health advances, idiopathic male infertility is a challenging condition with no identifiable cause, thereby complicating its diagnosis and appropriate treatment. The World Journal of Men’s Health recently published a review article “Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility”.
Oxidative stress is one of the major contributors to male infertility. Leukocytes and abnormal/immature spermatozoa produce seminal reactive oxygen species (ROS). These are also by-products of oxidative metabolic pathways and ATP…
