Treating epilepsy in women of reproductive age is a clinical challenge. Almost all women with epilepsy require anticonvulsant drugs for adequate control of their seizures, there is a high risk of teratogenicity associated with some antiepileptic drugs. Lamotrigine is one of the anti-epileptic drugs thought to have the lowest recorded risk, depending on dosage. The current article describes a new study in line with this fact that the increased risk of having a baby with a malformation may not be significantly higher for women who are taking lamotrigine.
Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. The recent study evaluated the effect of antenatal lamotrigine exposure, on short- and long-term pediatric outcome. Study design The study included children of 83 epileptic women treated with lamotrigine during pregnancy, at a tertiary medical…
