Brugada Syndrome was first discovered in the year 1992. It is one of the rare heart conditions leading to arrhythmia and sudden deaths. It is usually inherent, but at times it can be seen in patients without any family history. General Description: The global prevalence of Brugada syndrome (BrS) is 0.5 in 1000 patients. The electric impulses become uncoordinated in people with this syndrome, leading to irregular heartbeat followed by reduced blood flow to the brain and heart, resulting in sudden deaths.
It occurs due to mutation in the sodium channel gene, sodium voltage-gated channel alpha subunit 5 (SCN5A). 1 The QT levels are seen to be normal in these patients. This condition is usually reported more in males than females. 2 BrS can be subdivided into: 3 Type I Type II Type III Signs and Symptoms: BrS is inherited in an autosomal dominant manner, i.e., one altered gene can be the…
