A 25-year-old woman with chronic schizophrenia is referred for evaluation of abnormal thyroid function tests after experiencing an acute exacerbation of psychosis. PMH: She has no prior history of thyroid dysfunction but several family members have been affected by autoimmune thyroid disease. In last three months, she has lost 8 kg and has noted insomnia, tachycardia, heat intolerance and irregular menses.
Physical examination: Anxious and restless Resting tachycardia (rate 120 beats/min) A tremor of extended fingers Bilateral lid lag and stare Warm moist skin Brisk reflexes An inpalpable thyroid gland Thyroid function test results: Free T4= 4.2 ng/dL (pmol/L) TSH< 0.01 micro U/L Thyroglobulin= 5ng/mL 24 hour radiodine uptake= 2 percent What is the most likely diagnosis in this case? *This case is from Docplexus Editorial Team for educative purpose only Source: Endocrine fellows…
