Gilbert’s syndrome is a harmless liver condition with elevated bilirubin level. It is also named as constitutional hepatic dysfunction and familial nonhemolytic jaundice. GS is a common genetic liver disorder and found in almost 3-12% population. This article focuses on few clinical and pharmacological implications of the Gilbert’s syndrome. In medical terminology, GS is known an ‘unconjugated hyperbilirubinemia’. It is quite common and found in almost 3-12% population.
Probably one will have it but he might not be aware that he is having it. Mostly routine blood test indicating elevated bilirubin level reveals presence of GS. Males are more prone to GS than females. Their mean bilirubin concentrations are higher in GS as compared to females. It was first described by Gilbert and Lereboullet in 1901. They explained it as a syndrome of benign, periodic but chronic jaundice occurring…
