Extremely preterm newborns with baro/volutrauma and lung disease require prolonged respiratory support for survival. Corticosteroids, especially dexamethasone sodium phosphate, are generally used to reduce respiratory support requirements and mediate extubation in such newborns. Treatment with dexamethasone is usually started at 28 days with a six-week regimen for treating bronchopulmonary dysplasia (BPD) in preterm newborns.
However, the treatment causes left ventricular hypertrophy, hypertension, and outlet obstruction in newborns. Here is a quick question on dexamethasone treatment for extremely preterm newborns!