An 80-year-old woman presented with an 8-month history of an eventually growing, painful tumor on her right buttock. The patient mentioned a significant history of chronic kidney disease (CKD) and genital herpes simplex virus (HSV). Biopsy reports were suggestive of non-infectious, granulomatous ulcers. The patient was treated with oral antibiotics, intralesional steroids, topical steroids, and immunomodulators, but no significant improvement was observed.
On follow-up, physical examination revealed a 57 cm verrucous, exophytic tumor with scant yellow drainage on the right medial buttock extending to the perianal skin. An incisional biopsy of the lesion showed epithelial hyperplasia, ulceration, and focal multinucleated keratinocytes. What would be the probable disease condition in the above-mentioned case? Squamous cell carcinoma CD30-positive primary cutaneous anaplastic large cell…
