A 27-year-old male patient presented with epigastric pain and burning sensation. He is an alcoholic and smokes occasionally. His past or family history was not contributory. A provisional diagnosis of gastroesophageal reflux disease was made and followed by gastroscopy to rule out gastric ulcer or gastric neoplasm. Gastroscopy revealed a polypoidal lesion in the antrum of the stomach which was biopsied.
On gross examination, multiple, tiny grey-white soft tissue bits were seen. On microscopy, polypoidal growth, lined by epithelial cells showing scalloping of the margins was noted. These epithelial cells showed multilayering at places and atypia with enlargement of the nuclei. No areas of invasion of these atypical cells or glands (image attached)The slides were then submitted for the immunohistochemical (IHC) study for Ki-67, which showed classical staining pattern of serrated adenoma…
