Synopsis Overweight and obesity during maternity are associated with well-recognized pregnancy complications. Antenatal dietary and lifestyle interventions have a modest effect on gestational weight gain without affecting pregnancy outcomes. The aim of the present study is to assess the effects on maternal and infant outcomes of antenatal metformin given in addition to dietary and lifestyle advice among overweight and obese pregnant women. This week’s “ Journal Watch ” discusses a randomized trial from the Lancet Diabetes & Endocrinology, “ Effect of metformin in addition to dietary and lifestyle advice for pregnant women who are overweight or obese: the GRoW randomised, double-blind, placebo-controlled trial ”.
2018 Authors: JM Dodd, et. al. Key Takeaways Metformin, when used in obese pregnant women, does not improve pregnancy and birth outcomes. Objective: The aim was to assess the…
