Vasovagal syncope is also known as neuro-cardiogenic syncope. Reflex (neurally mediated) syncope is a transient loss of consciousness due to a reflex response that encompasses vasodilatation and/or bradycardia (rarely tachycardia), leading to systemic hypotension and cerebral hypoperfusion, particularly in the sitting/ upright position. Types of reflex syncope include vasovagal syncope, situational syncope, carotid sinus syncope, and atypical forms. Vasovagal syncope is the most common cause of syncope affecting nearly 20% of the population.

The diagnosis is usually suggested by a specific history with well-known triggers. The diagnosis can also be made by exclusion of other causes of syncope and by a characteristic response to upright tilt table testing (Hut tilt test). Pathogenesis: Both neural (Bezold-Jarisch and carotid sinus reflexes) and endogenous chemical pathways are thought to…