Optimal management of eosinophilic lung disease presentations targets the underlying cause when identifiable, and the urgency of management is dictated by the presence or absence of end-organ manifestations. Here’s an interesting case challenge for you! Case history A 44-year-old woman with a history of asthma, allergic rhinitis, and chronic sinusitis had received treatment for chronic progressive dyspnea with exertion, sinus congestion, and wheezing. There was no evidence of weight loss, fevers, chills, hemoptysis, sick contacts, smoking, or vaping. She had visited Costa Rica as a young adult.
She was healthy until four years ago when she experienced shortness of breath, cough, and sinus infections. CT scans of the sinuses revealed pan-sinusitis with polyps, and she was referred for polypectomy. She was diagnosed with asthma and was put on daily inhaled glucocorticoids. Over the next…