Recently, a clinical study has compared the efficacy of topical application of the injectable form of tranexamic acid (TXA) with anterior nasal packing (ANP) for the treatment of epistaxis in 124 patients who are on antiplatelet drugs (aspirin, clopidogrel, or both) and who presented to the emergency department (ED). The study was published in the journal of the “society for academic emergency medicine” and participants were randomized to receive topical TXA (500 mg in 5 mL) or ANP.

The study reported that epistaxis treatment with topical application of TXA resulted in faster bleeding cessation, less rebleeding at 1-week, shorter ED length of stay and higher patient satisfaction compared with ANP. According to your clinical practice, which is better in managing epistaxis: Topical Tranexamic Acid Or Nasal Packing?