Prophylactic use of antipyretic and analgesic drugs, initiated at the time of immunization and repeated 6 and 12 hours later, sometimes can reduce immune responses to infant vaccines, warranting judicious use was reported in a recently published study in the journal Pediatrics & Child Health. Recently, reducing pain during childhood immunizations has received greater attention making the experience more benign. The prophylactic administration of acetaminophen or ibuprofen is not recommended among pain-reducing strategies.
In some conditions including response to a previous postimmunization fever, prophylactic administration of antipyretic/analgesic drugs is undertaken by parents or immunizers to prevent or reduce adverse events. These drugs are typically started at the time of immunization and repeated about 6 and 12 hours after immunization. This three-dose prophylaxis can reduce the…
