Some patients with focal cerebral calcification (FCC) have no seizure or a benign course of epilepsy, whilst others with a similar lesion have uncontrolled epilepsy. Cranial computed tomography (CT) in patients with partial seizures with or without secondary generalisation often reveals single or multiple small (<10 mm) calcified lesions labelled as focal cerebral calcifications (FCCs). The most common etiology of FCC is cysticercosis. Other causes of FCC include healed tuberculoma, fungal granuloma or small calcified AV malformation.
About 16% to 45% of cysticercosis granuloma end up as calcification. The prognosis of seizures is worse if the lesions calcify as compared to those showing complete resolution. Even in patients with FCC-related epilepsy, some have a benign course while others have multiple seizures which may be difficult to control even with anti-epileptic drugs (AEDs). In…
