Summary Preterm birth affects foveal development and microstructural deviations associated with low gestational age. Although the deviations described using optical coherence tomography (OCT) are related to retinopathy of prematurity (ROP) and its treatment, the signs of foveal immaturity exist in children even without a history of ROP.

A recent study published in Eye has investigated whether any OCT parameters can be used as markers of abnormal foveal maturation. Study objectives Evaluate the linkages of foveal OCT parameters reflecting topography and microstructure in extreme preterm without retinopathy of prematurity (EPT-NoROP) when compared to control Estimate the proportion of EPT-NoROP eyes at the foveal center that are within normal limits Analyze relations between OCT parameters at the foveal center Findings The majority of cases of EPT-NoROP eyes had signs of foveal immaturity…