Case presentation A 62-year-old man developed progressive dysphagia and lost 2.5 kg over six months. He has had chronic gastroesophageal reflux disease for at least ten years and was taking an over-the-counter proton pump inhibitor. He has moderate hypertension that is well controlled with medication. He is moderately anemic (hemoglobin 11 g/dL), and because his anemia was unexplained and unexpected, he was referred to a gastroenterologist. Examination Upper and lower endoscopies were performed.
Colonoscopy was normal, but esophago-gastro-duodenoscopy showed a large mass located at the gastroesophageal junction (GEJ) extending to the proximal cardia. Several biopsies were performed, and the mass was identified as a poorly differentiated adenocarcinoma. A computed tomography (CT) scan revealed a GEJ mass, a 2-cm right lung mass, and 2 >1 cm liver masses. Source: Medscape ##Disclaimer##…