All current guidelines on the prevention of CVD in clinical practice recommend the assessment of total CAD or CV risk, because atherosclerotic CVD is usually the product of a number of risk factors, and prevention of CVD in a given person should be adapted to his/her total CV risk: the higher the risk, the more intense the action should be. New Information: CV Risk categories Very high Risk : “ all patients with documented CVD clinical or unequivocal on imaging, DM with target organ damage or with a major risk factor, severe CKD, SCORE* ≥10%” High Risk : “ Markedly elevated single risk factors such as Familial Hypercholesterolemia or Severe hypertension, most of other people with DM, Moderate CKD, SCORE ≥ 5% and <10%” Moderate and Low Risk : SCORE ≥1% and <5% and SCORE<1% respectively LDL-C targets: The targeted approach to lipid management is primarily aimed at reducing LDL-C.

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