Guillain-Barre syndrome (GBS) consists of a group of neuropathic conditions characterized by progressive weakness and diminished or absent myotatic reflexes. The syndrome is believed to result from an immune response that attacks nerve tissue. Although GBS is uncommon, early diagnosis and prompt medical attention may significantly improve outcomes. The most common form of GBS is a progressive motor weakness, usually beginning in the legs and advancing proximally. The diagnostic criteria for GBS include progressive, relatively symmetrical weakness with decreased or absent myotatic reflexes.
Epidemiology The incidence of GBS increases steadily from 0.62 per 100,000 persons in younger than nine years to those of 80 to 89 years of age. The male-to-female ratio is 3:2. Several infections have been implicated in the development of GBS. About two-thirds of patients with the disease report…
