Gynecomastia is a relatively common disorder. Its causes vary from benign physiologic processes to rare neoplasms. If gynecomastia is in its severe form, then medical management is indicated, and if the medical therapy is ineffective, surgical therapy is indicated. The current article describes the medical management of gynecomastia.
Medical management of gynecomastia is indicated when it is severe and does not have a treatable underlying cause. Medical management of gynecomastia It involves the following classes of drugs- Androgens (testosterone, dihydrotestosterone, danazol) Anti-estrogens (clomiphene citrate, tamoxifen) Aromatase inhibitors such as letrozole and anastrozole. If there is established gynecomastia, even testosterone treatment of hypogonadal men with gynecomastia fails to produce breast regression. In fact, treatment with testosterone may cause the side effect of…