In the past 50 years, there have been few changes in male contraception compared with the range of options available to women. The list starts with the use of condoms and ends in Vasectomy . Complete suppression of spermatogenesis can be achieved with injectable exogenous testosterone combined with a progestin, but the optimal regimen for use as a male contraceptive has not yet been established.
In a study of over 300 normal men receiving a long-acting parenteral regimen of testosterone undecanoate and norethisterone enanthate , 96 percent of continuing users had suppression of spermatogenesis within six months Contraceptive efficacy was excellent, and 95 percent of men had a recovery of normal spermatogenesis within one year of stopping treatment. The external safety review committee terminated the study early because it concluded the risks of continuing outweighed the possible…
