Chronic kidney disease (CKD) is the major microvascular complication often associated with debilitating conditions such as diabetes and cardiovascular disease. As CKD progresses there is a higher risk of comorbidities- like hyperphosphatemia- that become more severe and have a direct effect on the morbidity and mortality of the patients. Hyperphosphatemia is a condition in which phosphate in insufficiently filtered from the blood due to impaired functioning of kidneys.
It is evident that high serum phosphate levels can affect various biological processes- that play an essential role in the regulation of homeostasis- which in turn can lead to fatal conditions. In this regard, National Institute for Health and Care Excellence (NICE 2013) have summarized essential guidelines to assist medical professionals in the evidence-based management of hyperphosphatemia in with stage 4 or 5 CKD…
