Skin grafting has been a standard technique to heal wounds in burn cases. The success of a graft transplantation depends on capillary revascularization, lymphatic revascularization, and re-innervation. Failure in any of these steps may result in a graft failure. Laser Therapy is considered as a safe and effective therapeutic method.
Laser therapy is found to induce neovascularization and increase tissue perfusion. The positive effect of low-level laser therapy (LLLT) on tissue perfusion and wound healing are associated with several molecular mechanisms: Formation of reactive oxygen species Activation of ATPases Stimulation of calcium ion influx Increase in mRNA, protein synthesis and cellular proliferation Increase in VEGF and neovascularization Vaghardoost et al. (2018) studied the effects of low-level laser therapy on the healing process of donor site after skin graft surgery.…
