Patient history: A 54-year-old male with type 2 diabetes and early CKD stage 3 which was secondary to diabetic nephropathy comes for a follow-up. Blood pressure at home on losartan 50 mg/day and chlorthalidone 12.5 mg/day are 150/95 mm Hg and 154/94 mmHg, respectively, and there is no edema. Laboratory findings: Creatinine is 1.5 mg/dL, eGFR is 52 ml/min, and urine P/C ratio is 0.8.

What is the next most appropriate step for managing this patient? (Answer is posted in the comment section below!) *This Case Challenge is from the Editorial Team of Docplexus and is meant for educational purposes only. Source: Clinical Pearls in Renal Medicine