Emerging evidence suggests that mildly elevated body iron stores may contribute to the development of Type 2 diabetes, with men appearing to be at greater risk due to naturally higher iron accumulation than women. Iron is an essential micronutrient required for the formation of key proteins and enzymes, including hemoglobin, cytochromes, and peroxidases. However, excess iron can become harmful by promoting the formation of free radicals that may impair pancreatic beta-cell function and reduce insulin secretion .
Elevated iron levels have also been associated with reduced insulin sensitivity in tissues involved in glucose metabolism. A study led by researchers from the University of Eastern Finland, published in the Annals of Clinical Biochemistry, reported that men had a 61% higher prevalence and a 46% greater risk of developing Type 2 diabetes compared with women . The findings…
