A major challenge in the treatment of obesity has been the inability to target fat tissue at its exact location. The ability to precisely target fat cells and uncouple unhealthy fat formation from healthy fat metabolism could be a game changer in obesity treatment. Researchers from Columbia University have demonstrated a novel method to treat obesity using cationic nanomaterials, which can target specific areas of fat and prevent their unhealthy storage. Adipose tissue contains high amounts of negatively charged extracellular matrix to hold fat cells.
Researchers injected obese mice with positively charged nanomaterial, which spread throughout the tissue, specifically targeting visceral fat. Until now, there has been no way to specifically target visceral adipose fat. Current treatments for removing subcutaneous fat, such as liposuction, are invasive and damaging. This is a major…