Loss of taste, dry mouth, and mucosal lesions are well-known manifestations of COVID-19. However, none of the research to date has reported the involvement of the oral cavity in the pathophysiology of COVID-19. New research has revealed breakthrough findings suggesting the role of oral cells in COVID-19. Researchers at the National Institutes of Health and the University of North Carolina have found breakthrough evidence in the pathophysiology of COVID-19.
According to their research, published in the journal Nature Medicine , the SARS-CoV-2 virus infects cells in the mouth. The study was conducted by generating two single-cell RNA sequencing datasets of human minor salivary glands and gingiva. A total of 50 cell clusters were identified, of which 34 cell subpopulations were unique between salivary glands and gingiva. The saliva of the infected patients contained epithelial cells of the…
