Researchers at Brown University have developed a novel nanoparticle delivery system that releases its cargo only when it detects pathogenic bacteria. This new system could be used to treat infected wounds and also prove useful against antibiotic-resistant bacteria. The mechanism Conclusion The new drug delivery system presents an effective tool for treating infected wounds.
The controlled release of the therapeutic cargo effectively reduces the required dosage of the drug, reducing the side effects and potential for developing drug resistance, and the β-lactamase-sensitive matrix enables the release of drugs only in the presence of β-lactamase-producing bacteria. Can this system be used to treat infections caused due to other antibiotic-resistant bacteria? Source: ACS Applied Materials and Interfaces
