A common finding in patients with Chronic Kidney Disease (CKD) is Anemia. Its prevalence increases gradually as eGFR declines. The prevalence of renal a naemia depends on the size of the study and the selection of participants. Diabetic status increases the prevalence of anaemia in patients with CKD. Anaemia in CKD is due primarily to reduced production of erythropoietin in the kidney and secondarily to shortened red cell survival.
The investigation of renal anaemia requires the assessment of a variety of biological indices. Pathogenesis Anaemia in CKD is due primarily to reduced production of erythropoietin in the kidney and secondarily to shortened red cell survival. The main regulator of that process is erythropoietin, a glycoprotein hormone that circulates at about one hundredth of the concentration of most other hormones in the body. Erythropoietin (EPO) In humans, EPO is produced…
