Current evidence on the efficacy of photodynamic therapy (PDT) for patients with Barrett's esophagus with high-grade dysplasia (HGD) is adequate, provided that patients are followed up in the long term. There are no major safety concerns, although there is a risk of oesophageal stricture, and photosensitivity reactions are common. This procedure may be used in patients with Barrett's esophagus with HGD provided that normal arrangements are in place for clinical governance, consent, and audit.
Current evidence on the efficacy and safety of PDT in patients with Barrett's esophagus with either low-grade dysplasia (LGD) or no dysplasia is inadequate in quality and quantity, and the balance of risks and benefits is not clear. Therefore, for these patients, the procedure should be used only with special arrangements for clinical governance, consent and audit or research. PDT for Barrett's…
