The one-hour glucose level during an oral glucose tolerance test (OGTT) improves the early prediction of type 2 diabetes, according to results from the Botnia Prospective Study. In the study, 1-hour plasma glucose (PG) alone was almost as good as most other multivariate models, especially the combination of HbA1c and 1-hour PG, in predicting type 2 diabetes. One-hour plasma glucose showed the best predictive performance for type 2 diabetes, with 75% sensitivity, 68% specificity and 75% accuracy (by AUC), followed by the 30-min plasma glucose, with 62% sensitivity, 71% specificity and 71% accuracy. Both measures were more accurate than fasting plasma glucose or two-hour plasma glucose.
These results are reported online Nov. 15, 2018, in the Journal of Clinical Endocrinology and Metabolism . OGTT is a test commonly employed to screen for and diagnose type 2 diabetes and also to detect…
