Intracytoplasmic sperm injection (ICSI) is the most effective assisted reproductive procedure enabling fertilization in severe forms of male gamete dysfunction. The reliability of ICSI has allowed the expansion of its application to other forms of infertility rendering it the most popular assisted reproduction technology (ART) insemination method. However, there is still an incomplete picture of the risks associated with the use of this reproductive technique. This article outlines the risks associated with ICSI as a well-defined treatment for couples with severe male factor infertility.

The treatment of infertility has seen the development of revolutionary new assisted reproductive technologies. These highly complex technologies are used with increasing frequency in the treatment of couples around the world. As ART methods become the mainstream of infertility treatment, it has become…