Synopsis A recent clinical study demonstrates that occult urinary stones are present in about one-fifth of patients with asymptomatic primary hyperparathyroidism (PHPT) and is associated with higher urinary calcium and 1,25(OH) 2 D. This week's ' MED FACT ' discusses a clinical trial from Endocrine Research, “ Occult urolithiasis in asymptomatic primary hyperparathyroidism ”. 2018. Authors : Tay YK; Liu M; Bandeira L; Bucovsky M; Lee JA; Silverberg SJ; Walker MD.
Key Takeaways PHPT patients are at a high prevalence of occult urinary stones. Objective Study Type Participants To evaluate the risk factors associated with occult urolithiasis in asymptomatic PHPT Cross-Sectional Study 96 What Was The Need For This Study? Hypercalciuria has been associated with stone formation (symptomatic and silent) in PHPT. Studies also suggest that nephrolithiasis is associated with higher serum…