A 54-year-old woman presented with progressive, painless dysphagia. She had been suffering from this condition for the last three months. She also reported an unintentional weight loss of 25 lb and locking of jaws during eating. Periorbital rash, alopecia, and pain in the joints of her hand were also noted.
Physical examination Temporal wasting Inability to open mouth Bilateral sclerodactyly Laboratory studies ANA - Positive Barium swallow test - Normal EGD - Normal Biopsies of the esophagus - Significant for scattered neutrophils High-resolution esophageal manometry provided CK - 7,207 IU/L Anti-RNP - 57 Ehrlich units/mL RNA polymerase antibody - 20.4 U/mL High-resolution chest CT showed collagen vascular-associated interstitial lung disease (ILD). Edema and inflammation were observed in the MRI scans of the lower extremities. What can be the probable diagnosis for this patient? *This…
