Case presentation An 11-year-old boy with Autism spectrum disorder, intractable epilepsy, and Dravet syndrome due to SCN1A gene mutation, presented with complaints of lethargy, reduced oral intake, and weight loss of seven pounds for five days. His mother denied any fever, abdominal pain, vomiting, headache, or sick contacts, and his last seizure was six months back. History Previous attempts to control seizures with levetiracetam, clobazam have failed. The patient had a vagus nerve stimulator placed at the age of five. He showed developmental delays and had speech and learning difficulties.
No medical history of hematologic disorders was reported. The boy had no family history for seizures, developmental, or bleeding disorders. Current medication The boy had been taking valproic acid: 31 mg/kg/day, lacosamide: 7 mg/kg/day for seizures for the past eight years. Physical examination…
