Obesity is well documented to have negative effects on human organs, inducing several chronic illnesses such as diabetes, hypertension, fatty liver disease, and atherosclerosis. A team of researchers from the University of Hong Kong has discovered a novel mechanism that explains how fat impairs skeletal muscle function and offers a possible cure for obesity. The outcomes of the study were recently published in Autophagy. Researchers created a specific obesified mouse model by deleting the brain-derived neurotrophic factor (BDNF) gene from their skeletal muscle primarily to explore the functional effects of obesity on the skeletal muscles.
BDNF was first discovered to be a crucial growth factor for the survival and activity of neurons. Obesity was observed to have lowered the quantity of BDNF in mice's skeletal muscle for the first time. Researchers have also discovered that when mice…
