Rheumatic fever (RF) is an immunologically mediated inflammatory disease, that occurs as a delayed sequel to a group of streptococcal throat infection. The condition is witnessed in genetically susceptible individuals. The article tries to provide insights about this inflammatory disease condition. Rheumatic fever is one of the complications that accompanies a streptococcal throat infection. The subsequent complication called chronic rheumatic heart disease (RHD), is still a major public health problem.
The condition is relatively serious as it is causes stroke, permanent damage to the heart, and death if left untreated. The condition usually appears in children between the ages of 5 and 15 and even in older children and adults. Aetiopathogenesis The pathogenic mechanisms involved in the development of RF remain unclear. However, it is evident that an abnormal humoral and cellular…
