Seminal plasma is a complex fluid consists of the secretions from the seminal vesicles, prostate, bulbourethral glands, and seminiferous tubule lumen. It is evidenced that seminal plasma often serves as a medium to transmit, protect, and nourish sperm after ejaculation up to fertilization. However, there is less evidence for its functional modulator role in sperm function. In this regard, a recent study published in the Basic and clinical andrology reported that seminal plasma proteome was associated with male fertility. Moreover, it was observed that different biological conditions or cellular phenotypes modify its pathways away from its homeostatic condition to different energy production pathways.

Source: Camargo M, Intasqui P, Bertolla RP. Understanding the seminal plasma proteome and its role in male fertility. Basic and clinical andrology. 2018 Dec;28(1):6.